What is Growth Hormone, Somatostatin and Growth Hormone Releasing Hormone (GHRH)?
The growth hormone, as the name suggests, is a hormone that is responsible for physical growth of the body. The human growth hormone [HGH] is released by the anterior pituitary gland, present just above the hypothalamus in the brain. The cells responsible for the release of the HGH are called the somatotrophs and the hormone released is often referred to as somatotropin.mk677
The hormone responsible for the release of the somatotropin is the GHRH or growth hormone releasing hormone. The GHRH sends signal to the hypothalamus, telling it about the requirement levels of HGH in the body and the brain responds by releasing HGH from the anterior pituitary.
The HGHis responsible for lateral growth of the body. The final height that a person attains post puberty is as a result of the action this hormone. The hormone is also responsible for regeneration of decayed cells and tissues. The youthful appearance of a person depends on the total quantity of fresh and regenerated cells in the body. It is the HGH that regulates this. The normal aging of the body leads to gradual decrease in the production of the HGH, as a result of which the “youth” fades away. If it were possible to continuously replace the depleted HGH in the body by adding it externally, it would have been possible to hold “youth” forever.
What are the benefits of Growth hormone?
Growth hormone mitigates, and may even reverse, many of the major effects of aging, such as muscle weakness, excess body fat deposits, poor skin and hair quality, energy depletion, diminished sex drive, and declining immune function.
Many vital internal organs of the body shrink with age and it’s the HGH restores back the efficiency and vigor into those organs. The heart, liver, kidneys, spleen, thymus and the thyroid gland are immensely dependent on this hormone. It is also responsible for the release of IGF [insulin like growth factors], that help optimize communication between the immune system, nervous system and the hormonal systems.
How does human recombinant growth hormone work
External administration of the hormone has been practiced for ages by doctors to repair genetic defects in children with depleted HGH. Earlier the hormones were extracted from the brains of dead people [cadaveric], but that often led to infections in the patient receiving the hormone externally. Later, the scientists devised a new method of producing the hormone. The bacterium E.Coli is now used for HGH production. The end product is called human recombinant GH.
External addition of the hormone helps the body by:
· Stimulating the Somatotrophs to release more natural GH.
· Stimulating the hypothalamus to produce GHRH [growth hormone releasing hormone]
· Stimulating the Pituitary to become more sensitive to the effects of the GHRH.
· Opposing the production of Somatostatin.